b.55.1.1


SCOP classification
 
Class: All beta proteins
Fold: PH domain-like barrel
Superfamily: PH domain-like
Family: Pleckstrin-homology domain (PH domain)



Family Members
 
Domain: d1v89a_ of protein: Rho-GTPase-activating protein 25 (KIAA0053) from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d2coda1 of protein: Centaurin-delta 1 from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d2r0db2 of protein: Grp1 from Species: Mouse (Mus musculus) [TaxId: 10090]
Domain: d2nz8b2 of protein: Triple functional domain protein TRIO from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d3t06e2 of protein: Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d1wi1a_ of protein: Calcium-dependent activator protein for secretion, CAPS from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d2zkmx3 of protein: Phospholipase C-beta-2 from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d1fhoa_ of protein: UNC-89 from Species: Nematode (Caenorhabditis elegans) [TaxId: 6239]
Domain: d1v88a_ of protein: Oxysterol binding protein-related protein 8 (ORP-8, KIAA1451) from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d1upra_ of protein: Phosphoinositol 3-phosphate binding protein-1, PEPP1 from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d1fb8a_ of protein: Dual adaptor of phosphotyrosine and 3-phosphoinositides DAPP1/PHISH from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d2cofa1 of protein: KIAA1914 from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d2otxb_ of protein: Src-associated adaptor protein Skap2 from Species: Mouse (Mus musculus) [TaxId: 10090]
Domain: d4kaxb_ of protein: automated matches from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d1u5dd_ of protein: Src kinase-associated phosphoprotein SKAP55 (SCAP1) from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d1wgqa_ of protein: FYVE, RhoGEF and PH domain containing protein 6, Fgd6 (KIAA1362) from Species: Mouse (Mus musculus) [TaxId: 10090]
Domain: d2fjub3 of protein: Phospholipase C-beta-2 from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d1x1ga1 of protein: Pleckstrin-2 from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d1v61a_ of protein: Rac/CDC42 GEF 6, alpha-pix from Species: Mouse (Mus musculus) [TaxId: 10090]
Domain: d2coca1 of protein: FYVE, RhoGEF and PH domain containing protein 3, FGD3 from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d1v5pa_ of protein: Tapp2 from Species: Mouse (Mus musculus) [TaxId: 10090]
Domain: d2ys1a_ of protein: automated matches from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d2x18h_ of protein: automated matches from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d1u29a_ of protein: Cytohesin 2 from Species: Mouse (Mus musculus) [TaxId: 10090]
Domain: d1v5ma_ of protein: SH2 and PH domain-containing adapter protein APS from Species: Mouse (Mus musculus) [TaxId: 10090]
Domain: d1zc4d_ of protein: automated matches from Species: Norway rat (Rattus norvegicus) [TaxId: 10116]
Domain: d1mpha_ of protein: beta-spectrin from Species: Mouse (Mus musculus), brain [TaxId: 10090]
Domain: d2i5fa_ of protein: Pleckstrin from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d1v5ua_ of protein: SET binding factor 1, Sbf1 from Species: Mouse (Mus musculus) [TaxId: 10090]
Domain: d1eaza_ of protein: Tapp1 from Species: Human (Homo sapiens) [TaxId: 9606]
Domain: d1droa_ of protein: beta-spectrin from Species: Fruit fly (Drosophila melanogaster) [TaxId: 7227]
Domain: d1rj2j2 of protein: Dbl's big sister, Dbs from Species: Mouse (Mus musculus) [TaxId: 10090]



Multiple structure based alignment (Multiprot)


Multiple Structure based Sequence alignment
Multiple Structure based Sequence alignment (HHAlign)
Integrated Structure-Sequence alignment (ClustalO)
Integrated Structure-Sequence alignment (HMMalign)


Phylogenetic Representation
Strucuture based Phylogenetic tree (Using SDM) Strucuture based Phylogenetic tree (Using TM)